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Cytogenetic and molecular findings in 75 clear cell renal cell carcinomas

1 May 2005

Abstract excerpt

Cytogenetic analysis of 75 clear cell renal cell carcinomas (RCC) from adult patients revealed abnormal karyotypes in 59 (79%) tumors. Among structural abnormalities, the most frequent were deletions and unbalanced translocations leading to loss of 3p (found in 68% of karyotypically abnormal tumors), followed by rearrangements of chromosomes 5 (in 37%) and 1 (in 20%). Fifteen unbalanced interchromosomal...

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PMID: 15809763
DOI: 10.3892/or.13.5.949

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