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Article

Role of plasma kallikrein in diabetes and metabolism.

Thrombosis and haemostasis - 1 Sept 2013

Feener E P, Zhou Q, Fickweiler W

Abstract excerpt

Plasma kallikrein (PK) is a serine protease generated from plasma prekallikrein, an abundant circulating zymogen expressed by the Klkb1 gene. The physiological actions of PK have been primarily attributed to its production of bradykinin and activation of coagulation factor XII, which promotes inflammation and the intrinsic coagulation pathway. Recent genetic, molecular, and pharmacological studies of PK have...

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Identifiers

PMID: 23676986
DOI: 10.1160/TH13-02-0179
PMCID: PMC3757113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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