Article
Combined application of behavior genetics and microarray analysis to identify regional expression themes and gene-behavior associations.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 17 May 2006
Letwin Noah E, Kafkafi Neri, Benjamini Yoav, Mayo Cheryl, Frank Bryan C, Luu Troung, Lee Norman H, Elmer Greg I
Abstract excerpt
In this report we link candidate genes to complex behavioral phenotypes by using a behavior genetics approach. Gene expression signatures were generated for the prefrontal cortex, ventral striatum, temporal lobe, periaqueductal gray, and cerebellum in eight inbred strains from priority group A of the Mouse Phenome Project. Bioinformatic analysis of regionally enriched genes that were conserved across all strains...
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