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Article

Absence of erythroblast macrophage protein (Emp) leads to failure of erythroblast nuclear extrusion.

The Journal of biological chemistry - 21 Jul 2006

Soni Shivani, Bala Shashi, Gwynn Babette, Sahr Kenneth E, Peters Luanne L, Hanspal Manjit

Abstract excerpt

In mammals, the functional unit for definitive erythropoiesis is the erythroblastic island, a multicellular structure composed of a central macrophage surrounded by developing erythroblasts. Erythroblast-macrophage interactions play a central role in the terminal maturation of erythroblasts, including enucleation. One possible mediator of this cell-cell interaction is the protein Emp (erythroblast macrophage...

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PMID: 16707498
DOI: 10.1074/jbc.M603226200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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