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Article

Increased level of DJ-1 in the cerebrospinal fluids of sporadic Parkinson's disease.

Biochemical and biophysical research communications - 7 Jul 2006

Waragai Masaaki, Wei Jianshe, Fujita Masayo, Nakai Masaaki, Ho Gilbert J, Masliah Eliezer, Akatsu Hiroyasu, Yamada Tatsuo, Hashimoto Makoto

Abstract excerpt

DJ-1 is an antioxidant protein whose loss of function by gene mutations has been linked to familial Parkinson's disease (PD). The main objective of the present study was to determine if this molecule was also involved in the pathogenesis of sporadic PD. For this purpose, quantitative immunoblot assays were performed to evaluate DJ-1 in cerebrospinal fluids (CSF) collected from sporadic PD patients (n=40) and...

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Source

Identifiers

PMID: 16707095
DOI: 10.1016/j.bbrc.2006.05.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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