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Article

DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

15 Feb 2010

Abstract excerpt

Biomarkers are urgently needed for the diagnosis and monitoring of disease progression in Parkinson's disease. Both DJ-1 and alpha-synuclein, two proteins critically involved in Parkinson's disease pathogenesis, have been tested as disease biomarkers in several recent studies with inconsistent results. These have been largely due to variation in the protein species detected by different antibodies, limited...

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PMID: 20157014
DOI: 10.1093/brain/awq008

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