Article
Homer proteins: implications for neuropsychiatric disorders.
Current opinion in neurobiology - 1 Jun 2006
Szumlinski Karen K, Kalivas Peter W, Worley Paul F
Abstract excerpt
Homer proteins regulate signal transduction, synaptogenesis and receptor trafficking, in addition to maintaining and regulating extracellular glutamate levels in limbo-corticostriatal brain regions. Converging preclinical observations indicate a potential role for both immediate early gene Homer isoforms and constitutively expressed Homer isoforms in behavioral pathologies associated with neuropsychiatric...
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