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Article

Mutagenesis studies on the N-terminus and Thr54 of Naja naja atra (Taiwan cobra) chymotrypsin inhibitor.

The protein journal - 1 Jun 2006

Yan Fang-Jiun, Chen Ching-Ping, Cheng Yun-Ching, Chang Long-Sen

Abstract excerpt

Ala-screening mutagenesis studies on Arg1, Pro2, Arg3, Phe4 and Thr54 of Naja naja atra (Taiwan cobra) chymotrypsin inhibitor showed that inhibitory potency and gross conformation of the mutants were not significantly different from those of wild-type inhibitor. Nevertheless, the R1A mutant had an appreciable decrease in the structural stability underlying thermal unfolding and urea-induced denaturation....

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Identifiers

PMID: 16703468
DOI: 10.1007/s10930-006-9009-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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