Article
A 40-basepair VNTR polymorphism in the dopamine transporter (DAT1) gene and the rapid response to antidepressant treatment.
The pharmacogenomics journal - 1 Feb 2007
Kirchheiner J, Nickchen K, Sasse J, Bauer M, Roots I, Brockmöller J
Abstract excerpt
Finding predictors of the response to antidepressant therapy is a major goal of molecular psychiatry. The genes encoding the serotonin (SERT) and dopamine (DAT1) transporters are among the possible candidate genes modulating an individual's antidepressant response. In a naturalistic prospective cohort study with a total of 190 fully assessed patients, improvement of depression symptoms during the 3 weeks...
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