Article
Loss-of-function alleles of the JIL-1 kinase are strong suppressors of position effect variegation of the wm4 allele in Drosophila.
Genetics - 1 Aug 2006
Lerach Stephanie, Zhang Weiguo, Bao Xiaomin, Deng Huai, Girton Jack, Johansen Jørgen, Johansen Kristen M
Abstract excerpt
In this article we show that hypomorphic loss-of-function alleles of the JIL-1 histone H3S10 kinase are strong suppressors of position effect variegation (PEV) of the wm4 allele and that lack of JIL-1 activity can counteract the effect of the dominant enhancer Evar2-1 on PEV.
Topics
- Alleles
- Animals
- Drosophila
- Drosophila Proteins
- Genes, Dominant
- Genes, Suppressor
- Protein Serine-Threonine Kinases