Article
Kdr allelic variation in pyrethroid resistant mosquitoes, Culex quinquefasciatus (S.).
Biochemical and biophysical research communications - 30 Jun 2006
Xu Qiang, Wang Haichuan, Zhang Lee, Liu Nannan
Abstract excerpt
The loss of target site sensitivity to insecticides resulting from a substitution of leucine to phenylalanine, termed the kdr mutation, in the voltage-gated sodium channel of the insect nervous system is known to be important in insecticide resistance. However, little is known about the molecular basis of the genotype and kdr-mediated resistance phenotype relationship. This study investigated whether the...
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