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Article

Sodium channel genes and their differential genotypes at the L-to-F kdr locus in the mosquito Culex quinquefasciatus.

Biochemical and biophysical research communications - 22 Apr 2011

Xu Qiang, Tian Li, Zhang Lee, Liu Nannan

Abstract excerpt

The para-type sodium channel in insects is the primary target of pyrethroid and DDT insecticides. However, modifications in the target protein structure such as point mutations or substitutions, resulting from single nucleotide polymorphisms (SNP), cause insensitivity of the insect's nervous system to pyrethroids and DDT and, in turn, result in insecticide resistance. Among these mutations, substitution of...

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Identifiers

PMID: 21419752
DOI: 10.1016/j.bbrc.2011.03.060
PMCID: PMC3134871

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DDT

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