Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The molecular biology of knockdown resistance to pyrethroid insecticides.

Insect biochemistry and molecular biology - 1 Jun 2003

Soderlund D M, Knipple D C

Abstract excerpt

The term "knockdown resistance" is used to describe cases of resistance to diphenylethane (e.g. DDT) and pyrethroid insecticides in insects and other arthropods that result from reduced sensitivity of the nervous system. Knockdown resistance, first identified and characterized in the house fly (Musca domestica) in the 1950's, remains a threat to the continued usefulness of pyrethroids in the control of many pest...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Genes, Insect
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insecta

Share to Insecticide Resistance

Share to Protein Structure, Tertiary

Share to Pyrethrins

Share to Sodium Channels

Source

Identifiers

PMID: 12770575
DOI: 10.1016/s0965-1748(03)00023-7

Genes

DDT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The molecular biology of knockdown resistance to pyrethroid insecticides.PMID 12770575Read ↗

Knockdown resistance to DDT and pyrethroids in the house fly (Diptera: Muscidae): from genetic trait to molecular mechanism.Semantic proximity Read ↗

Identification of mutations in the housefly para-type sodium channel gene associated with knockdown resistance (kdr) to pyrethroid insecticides.Semantic proximity Read ↗

Knockdown resistance to DDT and pyrethroids: from target-site mutations to molecular modelling.Semantic proximity Read ↗

Recent advances in the study of knockdown resistance mutations in Aedes mosquitoes with a focus on several remarkable mutations.Semantic proximity Read ↗

Point mutations in the Drosophila sodium channel gene para associated with resistance to DDT and pyrethroid insecticides.Semantic proximity Read ↗

Sodium Channel Mutations and Pyrethroid Resistance in Aedes aegyptiSemantic proximity Read ↗

The molecular interactions of pyrethroid insecticides with insect and mammalian sodium channels.Semantic proximity Read ↗

Knockdown resistance in mosquito vectors: Molecular mechanisms, global spread, and future directions for sustainable vector control.Semantic proximity Read ↗

Tight genetic linkage between the kdr insecticide resistance trait and a voltage-sensitive sodium channel gene in the house fly.Semantic proximity Read ↗

Sodium channel gene expression associated with pyrethroid resistant house flies and German cockroaches.Semantic proximity Read ↗

The L1014F Point Mutation in the House Fly Vssc1 Sodium Channel Confers Knockdown Resistance to PyrethroidsSemantic proximity Read ↗

Overcoming super-knock down resistance (super-kdr) mediated resistance: multi-halogenated benzyl pyrethroids are more toxic to super-kdr than kdr house flies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.