Sodium channel gene expression associated with pyrethroid resistant house flies and German cockroaches.

doi:10.1016/j.gene.2006.04.013

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Article

Sodium channel gene expression associated with pyrethroid resistant house flies and German cockroaches.

Gene - 1 Sept 2006

Xu Qiang, Wang Haichuan, Zhang Lee, Liu Nannan

Abstract excerpt

The voltage-gated sodium channels of the insect nervous system are the primary target of DDT and pyrethroid insecticides. The loss of target site sensitivity to insecticides resulting from a substitution of leucine to phenylalanine, termed the L-to-F kdr mutation, in the sodium channel of the insect nervous system is known to be important in insecticide resistance. Yet, little is known about the molecular basis...

Topics

Alleles
Animals
Cockroaches
Culex
DNA
Female
Gene Expression
Genetic Variation
Houseflies
Insect Proteins
Insecticide Resistance
Insecticides
Leucine
Male
Mutation
Phenylalanine
Polymorphism, Single Nucleotide
Pyrethrins

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Open in PubMed

Identifiers

PMID: 16828989
DOI: 10.1016/j.gene.2006.04.013

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