Article
Close-up and genomic views of the yeast vacuolar H+-ATPase.
Journal of bioenergetics and biomembranes - 1 Dec 2005
Kane Patricia M
Abstract excerpt
The yeast V-ATPase has emerged as an excellent model for other eukaryotic V-ATPases. In this review, recent biochemical and genomic studies of the yeast V-ATPase are described, with a focus on: 1) the role of V(1) subunit H in coupling ATP hydrolysis and proton pumping and 2) identification of the full set of yeast haploid deletion mutants that exhibit the pH and calcium-sensitive growth characteristic of loss of...
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