Article
A journey from mammals to yeast with vacuolar H+-ATPase (V-ATPase).
Journal of bioenergetics and biomembranes - 1 Aug 2003
Nelson Nathan
Abstract excerpt
The vacuolar H+-ATPase (V-ATPase) is one of the most fundamental enzymes in nature. It functions in almost every eukaryotic cell and energizes a wide variety of organelles and membranes. V-ATPase has a structure and mechanism of action similar to F-ATPase and several of their subunits probably evolved from common ancestors. In eukaryotic cells, F-ATPase is confined to the semiautonomous organelles, chloroplasts...
Read the complete abstract on PubMedTopics
- Animals
- Biological Transport
- Cloning, Molecular
- Humans
- Mutation
- Protein Subunits
- Proton-Translocating ATPases
