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Article

Healthy Neonates Possess a CD56-Negative NK Cell Population with Reduced Anti-Viral Activity.

PloS one - 1 Jan 2013

Jacobson Amanda, Bell Frank, Lejarcegui Nicholas, Mitchell Caroline, Frenkel Lisa, Horton Helen

Abstract excerpt

BACKGROUND: Neonatal Natural Killer (NK) cells show functional impairment and expansion of a CD56 negative population of uncertain significance. METHODS: NK cells were isolated from cord blood and from adult donors. NK subpopulations were identified as positive or negative for the expression of CD56 and characterized for expression of granzyme B and surface markers by multi-parameter flow cytometry. Cell function...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23805324
DOI: 10.1371/journal.pone.0067700
PMCID: PMC3689709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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