Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of Plasmodium falciparum cytochrome b gene mutations in isolates imported from Africa, and implications for atovaquone resistance.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Oct 2006

Berry A, Senescau A, Lelièvre J, Benoit-Vical F, Fabre R, Marchou B, Magnaval J F

Abstract excerpt

The atovaquone resistance of malaria parasites correlates with mutations in the cytochrome b gene. We sequenced the Plasmodium falciparum cytochrome b gene of 135 African isolates. Our data showed a high mutation rate (8.9%); however, the risk of emergence spreading of atovaquone-resistant P. falciparum strains could be limited.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Africa
Share to Antimalarials
Share to Cytochromes b

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Emigration and Immigration

Share to Malaria, Falciparum

Share to Plasmodium falciparum

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 16690094
DOI: 10.1016/j.trstmh.2006.02.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of Plasmodium falciparum cytochrome b gene mutations in isolates imported from Africa, and implications for atovaquone resistance.PMID 16690094Read ↗

Molecular surveillance of mutations in the cytochrome b gene of Plasmodium falciparum in Gabon and Ethiopia.Semantic proximity Read ↗

Mutations in the cytochrome b gene of Plasmodium berghei conferring resistance to atovaquone.Semantic proximity Read ↗

Mitochondrial heteroplasmy is responsible for Atovaquone drug resistance in <i>Plasmodium falciparum</i>Semantic proximity Read ↗

Mutation underlying resistance of Plasmodium berghei to atovaquone in the quinone binding domain 2 (Qo(2)) of the cytochrome b gene.Semantic proximity Read ↗

Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site.Semantic proximity Read ↗

Parasites resistant to the antimalarial atovaquone fail to transmit by mosquitoes.Semantic proximity Read ↗

Molecular characterization of the cytochrome b gene and in vitro atovaquone susceptibility of Plasmodium falciparum isolates from Kenya.Semantic proximity Read ↗

Cytochrome b mutations that modify the ubiquinol-binding pocket of the cytochrome bc1 complex and confer anti-malarial drug resistance in Saccharomyces cerevisiae.Semantic proximity Read ↗

Cytochrome b Mutation Y268S Conferring Atovaquone Resistance Phenotype in Malaria Parasite Results in Reduced Parasite bc1 Catalytic Turnover and Protein ExpressionSemantic proximity Read ↗

Mutations in cytochrome b resulting in atovaquone resistance are associated with loss of fitness in Plasmodium falciparum.Semantic proximity Read ↗

Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene.Semantic proximity Read ↗

Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.