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Article

Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site.

Antimicrobial agents and chemotherapy - 1 Aug 2000

Korsinczky M, Chen N, Kotecka B, Saul A, Rieckmann K, Cheng Q

Abstract excerpt

Atovaquone is the major active component of the new antimalarial drug Malarone. Considerable evidence suggests that malaria parasites become resistant to atovaquone quickly if atovaquone is used as a sole agent. The mechanism by which the parasite develops resistance to atovaquone is not yet full...

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Identifiers

PMID: 10898682
DOI: 10.1128/AAC.44.8.2100-2108.2000
PMCID: PMC90020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10898682-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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