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Article

Screening methods for identifying pharmacological chaperones.

Molecular bioSystems - 28 Mar 2017

Shin Min Hyeon, Lim Hyun-Suk

Abstract excerpt

Protein folding is crucial for most proteins to achieve their correct three-dimensional conformations and function properly. Defects in protein folding frequently caused by mutations lead to a range of protein misfolding diseases, including Alzheimer's disease, Parkinson's disease, cystic fibrosis, amyloidosis, Gaucher disease, etc. One approach to treat these devastating diseases would be to use pharmacological...

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Identifiers

PMID: 28265599
DOI: 10.1039/c6mb00866f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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