Article
[Pharmacological chaperones: a potential therapeutic treatment for conformational diseases].
Medecine sciences : M/S - 1 Jan 2000
Mendre Christiane, Mouillac Bernard
Abstract excerpt
Many genetic and neurodegenerative diseases in humans result from protein misfolding and/or aggregation. These diseases are named conformational diseases. As a result, the misfolded non functional proteins are rejected and misrouted by the cellular quality control system, and cannot play their en...
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