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Article

Recombination activating genes (RAG) in lymphoma development.

Cell cycle (Georgetown, Tex.) - 1 May 2006

Haines Brian B, Ryu Chun Jeih, Chen Jianzhu

Abstract excerpt

The recombination activating genes (RAG) play a central role in the generation of a diverse immune repertoire by mediating DNA recombination events at antigen receptor loci in developing B and T lymphocytes. However, inappropriate RAG activity throughout the genome has been implicated in a large variety of human and mouse lymphomas. Mechanisms by which RAG can provoke or perpetuate lymphoma include deregulation...

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Identifiers

PMID: 16687916
DOI: 10.4161/cc.5.9.2732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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