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Article

Genetic Mouse Models of Lymphomas.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2025

Knittel Gero, Reinhardt Hans Christian

Abstract excerpt

Mouse models are an indispensable tool in lymphoma research. Here, we focus on the utilization of genetically engineered mouse models as preclinical avatars in lymphoma research. We describe lymphoma-relevant alleles and allele combinations, as well as general considerations for model selection. We further illustrate concepts of gene targeting and model design and provide guidelines for breeding strategies and...

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PMID: 39424735
DOI: 10.1007/978-1-0716-4188-0_18

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