Article
A useful protocol for analyses of mutations of the epidermal growth factor receptor gene.
Oncology reports - 1 Jun 2006
Liu Dage, Nakano Jun, Ueno Masaki, Masuya Daiki, Nakashima Takashi, Yokomise Hiroyasu, Yube Kouichi, Huang Cheng-Long
Abstract excerpt
Recent studies have reported that mutations of the epidermal growth factor receptor (EGFR) gene are associated with the responsiveness of tyrosine kinase inhibitors (TKIs), which are molecular targets for non-small cell lung cancer (NSCLC). To provide genetic analyses for NSCLC patients, a simple and reliable method using paraffin-embedded materials is needed. The DEXPAT DNA extraction kit was used for DNA...
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