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Article

Utility of serum DNA and pyrosequencing for the detection of EGFR mutations in non-small cell lung cancer.

Cancer genetics - 1 Mar 2013

Akca Hakan, Demiray Aydın, Yaren Arzu, Bir Ferda, Koseler Aylin, Iwakawa Reika, Bagci Gulseren, Yokota Jun

Abstract excerpt

Mutations in the EGFR gene are critical determinants of treatment with EGFR tyrosine kinase inhibitors (TKIs) for non-small cell lung cancer (NSCLC) patients. DNA isolation from tumor samples usually requires surgery; therefore, we wanted to isolate DNA from circulating tumor cells by using the serum of NSCLC patients. This protocol was recently published. DNA was isolated from the serum of 52 Turkish NSCLC...

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Share to Adenocarcinoma
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

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Share to Neoplastic Cells, Circulating

Source

Identifiers

PMID: 23491080
DOI: 10.1016/j.cancergen.2013.01.005

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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