Article
Detection of epidermal growth factor receptor mutations in formalin fixed paraffin embedded biopsies in Malaysian non-small cell lung cancer patients.
Journal of biomedical science - 16 Apr 2013
Shi Yeen Tiffany Ng, Pathmanathan Rajadurai, Shiran Mohd Sidik, Ahmad Zaid Fattah Azman, Cheah Yoke Kqueen
Abstract excerpt
BACKGROUND: Somatic mutations of the epidermal growth factor receptor (EGFR) are reportedly associated with various responses in non-small cell lung cancer (NSCLC) patients receiving the anti-EGFR agents. Detection of the mutation therefore plays an important role in therapeutic decision making. The aim of this study was to detect EGFR mutations in formalin fixed paraffin embedded (FFPE) samples using both...
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