Article
Common sequence variation in the VEGFA gene predicts risk of diabetic retinopathy.
Investigative ophthalmology & visual science - 1 Dec 2009
Abhary Sotoodeh, Burdon Kathryn P, Gupta Aanchal, Lake Stewart, Selva Dinesh, Petrovsky Nikolai, Craig Jamie E
Abstract excerpt
PURPOSE: Vascular endothelial growth factor (VEGF) is a multifunctional cytokine that plays a role in angiogenesis and microvascular permeability. This study was conducted to determine whether common sequence variation in the VEGFA gene plays a role in the development of diabetic retinopathy (DR). METHOD: Five hundred fifty-four subjects with diabetes mellitus (DM) including 190 type 1 DM (T1DM) and 364 type 2 DM...
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