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Article

Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.

American journal of physiology. Renal physiology - 1 Jun 2006

Malik B, Price S R, Mitch W E, Yue Q, Eaton D C

Abstract excerpt

Amiloride-sensitive epithelial Na+ channels (ENaC) play a crucial role in Na+ transport and fluid reabsorption in the kidney, lung, and colon. The magnitude of ENaC-mediated Na+ transport in epithelial cells depends on the average open probability of the channels and the number of channels on the apical surface of epithelial cells. The number of channels in the apical membrane, in turn, depends on a balance...

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Identifiers

PMID: 16682484
DOI: 10.1152/ajprenal.00432.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.PMID 16682484Read ↗

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