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Article

Adoptive T‐cell transfer in cancer immunotherapy

2 May 2006

Abstract excerpt

Adoptive T-cell therapy has definite clinical benefit in relapsed leukaemia after allogeneic transplant and in Epstein-Barr virus-associated post-transplant lymphoproliferative disease. However, the majority of tumour targets are weakly immunogenic self-antigens and success has been limited in part by inadequate persistence and expansion of transferred T cells and by tumour-evasion strategies. Adoptive...

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PMID: 16681825
DOI: 10.1111/j.1440-1711.2006.01441.x

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