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Ex vivo gene transfer for improved adoptive immunotherapy of cancer

17 Mar 2011

Abstract excerpt

Adoptive immunotherapy is an appealing approach to cancer treatment, with the potential for more precise targeting and reduced toxicity. While early clinical trial data using adoptive T cells against post-transplant virus-associated hematologic malignancies, lymphoma and melanoma have been promising, treating other solid tumors has proven to be more challenging. Adoptive lymphocytes have been genetically modified...

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PMID: 21415041
DOI: 10.1093/hmg/ddr102

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