Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunoregulatory T cells in cancer immunotherapy.

Expert opinion on biological therapy - 1 Dec 2002

Morse Michael A, Clay Timothy M, Mosca Paul, Lyerly H Kim

Abstract excerpt

Many of the tumour antigens targeted by active immunisation strategies are in fact self-antigens. Successful anticancer immunotherapy will therefore require not only potent methods of T cell activation, but also successful interference with mechanisms of immune tolerance that have evolved to prevent tissue destruction by autoreactive T cells. In addition to thymic deletion, anergy and skewing of T cell cytokine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Neoplasm
Share to CD4 Antigens
Share to Immunotherapy, Adoptive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms

Share to Phenotype

Share to Receptors, Interleukin-2

Share to T-Lymphocytes

Source

Identifiers

PMID: 12517262
DOI: 10.1517/14712598.2.8.827

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunoregulatory T cells in cancer immunotherapy.PMID 12517262Read ↗

Induced and natural regulatory T cells in human cancer.Semantic proximity Read ↗

Induced regulatory T cells in inhibitory microenvironments created by cancerSemantic proximity Read ↗

T lymphocytes against solid malignancies: winning ways to defeat tumoursSemantic proximity Read ↗

Regulatory T cells in cancer: where are we now?Semantic proximity Read ↗

Natural and Induced T Regulatory Cells in CancerSemantic proximity Read ↗

Vaccination with T cell-defined antigens.Semantic proximity Read ↗

Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humansSemantic proximity Read ↗

Control of autoimmunity by naturally arising regulatory CD4+ T cells.Semantic proximity Read ↗

Treating autoimmune disease by targeting CD8+T suppressor cellsSemantic proximity Read ↗

Does the Immune System Naturally Protect Against Cancer?Semantic proximity Read ↗

CD137-expressing regulatory T cells in cancer and autoimmune diseasesSemantic proximity Read ↗

CD8+ CD28- T regulatory lymphocytes inhibiting T cell proliferative and cytotoxic functions infiltrate human cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.