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Article

Pathogenesis, Diagnosis and Monitoring of Residual Disease in Acute Promyelocytic Leukaemia

1 Jan 2004

Abstract excerpt

The clinical course of acute promyelocytic leukaemia (APL) has changed over the last 25 years from one that was fatal for the majority of patients to representing one of the most curable subtypes of acute myeloid leukaemia. Besides improved supportive care this has mainly been achieved through the introduction of novel targeted therapies in the form of all-trans retinoic acid (ATRA) and arsenic trioxide that...

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Identifiers

PMID: 15179005
DOI: 10.1159/000077560

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