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Article

Utilization of molecular phenotypes to detect relapse and optimize the management of acute promyelocytic leukemia.

Clinical lymphoma, myeloma & leukemia - 1 Oct 2010

Hasan Syed Khizer, Lo-Coco Francesco

Abstract excerpt

Acute promyelocytic leukemia (APL) is characterized by a unique genetic aberration, the t(15;17) chromosome translocation. Translocation breakpoints are located within the promyelocytic leukemia (PML) locus on chromosome 15 and the retinoic acid receptor alpha (RARA) locus on chromosome 17. In the past 2 decades, critical advances have been made in understanding the molecular pathogenesis of APL. APL represents a...

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Source

Identifiers

PMID: 21115433
DOI: 10.3816/CLML.2010.s.027

Genes

PML
RARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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