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Article

Three-dimensional localization of divergent region 3 of the ryanodine receptor to the clamp-shaped structures adjacent to the FKBP binding sites.

The Journal of biological chemistry - 18 Apr 2003

Zhang Jing, Liu Zheng, Masumiya Haruko, Wang Ruiwu, Jiang Dawei, Li Fei, Wagenknecht Terence, Chen S R Wayne

Abstract excerpt

Of the three divergent regions of ryanodine receptors (RyRs), divergent region 3 (DR3) is the best studied and is believed to be involved in excitation-contraction coupling as well as in channel regulation by Ca(2+) and Mg(2+). To gain insight into the structural basis of DR3 function, we have determined the location of DR3 in the three-dimensional structure of RyR2. We inserted green fluorescent protein (GFP)...

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Identifiers

PMID: 12576471
DOI: 10.1074/jbc.M213164200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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