Article
Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.
Circulation research - 2 Mar 2001
Cribbs L L, Martin B L, Schroder E A, Keller B B, Delisle B P, Satin J
Abstract excerpt
During cardiac development, there is a reciprocal relationship between cardiac morphogenesis and force production (contractility). In the early embryonic myocardium, the sarcoplasmic reticulum is poorly developed, and plasma membrane calcium (Ca(2+)) channels are critical for maintaining both contractility and excitability. In the present study, we identified the Ca(V)3.1d mRNA expressed in embryonic day 14 (E14)...
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