Article
Phosphorylation at the hydrophobic site of protein kinase C Apl II is increased during intermediate term facilitation.
Neuroscience - 11 Aug 2006
Lim T, Sossin W S
Abstract excerpt
In Aplysia, persistent increases in synaptic strength are paralleled by the persistent activation of the novel protein kinase C Apl II. We raised a phosphospecific antibody against serine 725, the hydrophobic motif in protein kinase C Apl II. Phosphorylation of serine 725 increased in parallel to the persistent activation of the kinase. We expressed protein kinase C where this site was mutated to an alanine to...
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