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Article

Deficient protein kinase C activity in turnip, a Drosophila learning mutant.

The Journal of biological chemistry - 25 Aug 1991

Choi K W, Smith R F, Buratowski R M, Quinn W G

Abstract excerpt

The Drosophila mutant turnip was initially isolated based on poor learning performance (Quinn, W.G., Sziber, P.P., and Booker, R. (1979) Nature 277, 212-214). Here we show that turnip is dramatically reduced in protein kinase C (PKC) activity. In addition, turnip flies are deficient in phosphorylation of a 76-kDa head membrane protein (hereafter pp76) which is a major substrate for protein kinase C in homogenates...

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PMID: 1874743

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