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Article

Memory maintenance by PKMζ — an evolutionary perspective

1 Jan 2012

Abstract excerpt

Long-term memory is believed to be maintained by persistent modifications of synaptic transmission within the neural circuits that mediate behavior. Thus, long-term potentiation (LTP) is widely studied as a potential physiological basis for the persistent enhancement of synaptic strength that might sustain memory. Whereas the molecular mechanisms that initially induce LTP have been extensively characterized, the...

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PMID: 22986281
DOI: 10.1186/1756-6606-5-31

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