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Article

Mutation in the phosphorylation sites of MAP kinase blocks learning-related internalization of apCAM in Aplysia sensory neurons.

Neuron - 1 Jun 1997

Bailey C H, Kaang B K, Chen M, Martin K C, Lim C S, Casadio A, Kandel E R

Abstract excerpt

The synaptic growth that accompanies 5-HT-induced long-term facilitation of the sensory to motor neuron connection in Aplysia is associated with the internalization of apCAM at the surface membrane of the sensory neuron. We have now used epitope tags to examine the fate of each of the two apCAM isoforms (membrane bound and GPI-linked) and find that only the transmembrane form is internalized. This internalization...

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Share to Calcium-Calmodulin-Dependent Protein Kinases
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Identifiers

PMID: 9208859
DOI: 10.1016/s0896-6273(00)80331-1

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GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutation in the phosphorylation sites of MAP kinase blocks learning-related internalization of apCAM in Aplysia sensory neurons.PMID 9208859Read ↗

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