Article
Cancer progression by non-clonal chromosome aberrations.
Journal of cellular biochemistry - 15 Aug 2006
Heng Henry H Q, Bremer Steven W, Stevens Joshua, Ye Karen J, Miller Fred, Liu Gou, Ye Christine J
Abstract excerpt
The establishment of the correct conceptual framework is vital to any scientific discipline including cancer research. Influenced by hematologic cancer studies, the current cancer concept focuses on the stepwise patterns of progression as defined by specific recurrent genetic aberrations. This concept has faced a tough challenge as the majority of cancer cases follow non-linear patterns and display stochastic...
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