Article
Chromosome aberrations in solid tumors have a stochastic nature.
Mutation research - 30 Aug 2006
Castro Mauro A A, Onsten Tor G H, Moreira José C F, de Almeida Rita M C
Abstract excerpt
An important question nowadays is whether chromosome aberrations are random events or arise from an internal deterministic mechanism, which leads to the delicate task of quantifying the degree of randomness. For this purpose, we have defined several Shannon information functions to evaluate disorder inside a tumor and between tumors of the same kind. We have considered 79 different kinds of solid tumors with 30...
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