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Article

Development of handed body asymmetry in mammals.

Ciba Foundation symposium - 1 Jan 1991

Brown N A, McCarthy A, Wolpert L

Abstract excerpt

We have proposed a three step model for the specification of left-right in mammalian embryos. The fundamental assumption is that handedness is imparted by an asymmetrical molecule. Conversion of molecular asymmetry to the cellular level gives a property to one side of the embryo to bias an otherwise random generation of an asymmetrical gradient which can be interpreted by developing organs. Rat embryos, treated...

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PMID: 1666358
DOI: 10.1002/9780470514160.ch11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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