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Article

p38 MAP kinase drives the expression of mast cell-derived IL-9 via activation of the transcription factor GATA-1.

Molecular immunology - 1 Feb 2007

Stassen Michael, Klein Matthias, Becker Marc, Bopp Tobias, Neudörfl Christine, Richter Christoph, Heib Valeska, Klein-Hessling Stefan, Serfling Edgar, Schild Hansjörg, Schmitt Edgar

Abstract excerpt

Mast cells are able to produce a huge panel of mediators including the Th2-type cytokine IL-9, which is considered to be a key mediator for the pathogenesis of allergic asthma, but detailed information on the regulation of IL-9 transcription in mast cells has been scarce. Herein we provide eviden...

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Source

Identifiers

PMID: 16650898
DOI: 10.1016/j.molimm.2006.03.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16650898-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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