Article
Mast cell transcription factors--regulators of cell fate and phenotype.
Biochimica et biophysica acta - 1 Jan 2012
Tshori Sagi, Nechushtan Hovav
Abstract excerpt
Transcription factors have a key role in mast cell differentiation and response of differentiated mast cells to external stimuli. During differentiation of progenitor cells to mast cells, a role for different GATA transcription factors in combination with PU.1 expression and downregulation of C/EBPα has been described. Notch pathway has been proposed to have a role in mast cell development. The...
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