Article
Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2006
Zhang Huiping, Ozbay Fatih, Lappalainen Jaakko, Kranzler Henry R, van Dyck Christopher H, Charney Dennis S, Price Lawrence H, Southwick Steven, Yang Bao-Zhu, Rasmussen Ann, Gelernter Joel
Abstract excerpt
Genetic variation at the locus encoding the brain derived neurotrophic factor (BDNF) has been implicated in some neuropsychiatric disorders such as Alzheimer's disease (AD), affective disorders (AFDs), schizophrenia, and substance dependence. We therefore performed a mutation scan of the BDNF gene to identify novel gene variants and examined the association between BDNF variants and several neuropsychiatric...
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