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Article

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and its implication in executive functions in adult offspring of alcohol-dependent probands.

Alcohol (Fayetteville, N.Y.) - 1 Jun 2013

Benzerouk Farid, Gierski Fabien, Gorwood Philip, Ramoz Nicolas, Stefaniak Nicolas, Hübsch Bérengère, Kaladjian Arthur, Limosin Frédéric

Abstract excerpt

Impairment of executive functions (EFs) mediated by the prefrontal lobe is regarded as a cognitive endophenotype of alcohol dependence, being observed both in probands and in healthy offspring. Given its impact on the anatomy of the prefrontal cortex, the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism may well be involved in this specific endophenotype. Forty-six healthy adult children of...

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PMID: 23582695
DOI: 10.1016/j.alcohol.2013.03.001

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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