Article

Shortened lifespan and other age-related defects in bang sensitive mutants of <i>Drosophila melanogaster</i>

2018-07-27

Abstract excerpt

<h4>ABSTRACT</h4> Mitochondrial diseases are complex disorders that exhibit their primary effects in energetically active tissues. Damage generated by mitochondria is also thought to be a key component of aging and age-related disease. An important model for mitochondrial dysfunction is the bang sensitive (bs) mutants in Drosophila melanogaster . Although these mutants all show a striking seizure phenotype, seve...

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Literature Corpus work: 5a6caa99-24a0-53a0-b0fc-df2f79a41554
DOI: 10.1101/379321

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