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Article

Mitochondrial DNA mutations, energy metabolism and apoptosis in aging muscle.

Ageing research reviews - 1 May 2006

Dirks Amie J, Hofer Tim, Marzetti Emanuele, Pahor Marco, Leeuwenburgh Christiaan

Abstract excerpt

Locomotor functional decline and loss in muscle mass with age is virtually a universal characteristic that has been documented in several species, including worms, fruit flies, rodents, non-human primates and humans. The age-related loss of muscle mass and strength (sarcopenia) represents an important risk factor for disability and mortality in older subjects and has been linked with cellular energy deficit and...

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Identifiers

PMID: 16647308
DOI: 10.1016/j.arr.2006.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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