No evidence for association of OAS1 with type 1 diabetes in unaffected siblings or type 1 diabetic cases.

doi:10.2337/db05-1452

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Article

No evidence for association of OAS1 with type 1 diabetes in unaffected siblings or type 1 diabetic cases.

Diabetes - 1 May 2006

Smyth Deborah J, Cooper Jason D, Lowe Christopher E, Nutland Sarah, Walker Neil M, Clayton David G, Todd John A

Abstract excerpt

Type 1 diabetes is a common autoimmune disorder that is strongly clustered in families. As the sharing of alleles of the HLA class II genes cannot explain all of this aggregation, alleles of multiple other loci are involved. Recently, it was reported that an A/G splice-site single nucleotide polymorphism (SNP; rs10774671) in the OAS1 gene, encoding 2'5'-oligoadenylate synthetase, was associated with a protective...

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PMID: 16644715
DOI: 10.2337/db05-1452

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OAS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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