Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample.

doi:10.1016/j.drugalcdep.2007.08.015

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Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample.

Drug and alcohol dependence - 11 Jan 2008

Agrawal Arpana, Hinrichs Anthony L, Dunn Gerald, Bertelsen Sarah, Dick Danielle M, Saccone Scott F, Saccone Nancy L, Grucza Richard A, Wang Jen C, Cloninger C Robert, Edenberg Howard J, Foroud Tatiana, Hesselbrock Victor, Kramer John, Bucholz Kathleen K, Kuperman Samuel, Nurnberger John I, Porjesz Bernice, Schuckit Marc A, Goate Alison M, Bierut Laura J

Abstract excerpt

Dependence on alcohol and illicit drugs frequently co-occur. Results from a number of twin studies suggest that heritable influences on alcohol dependence and drug dependence may substantially overlap. Using large, genetically informative pedigrees from the Collaborative Study on the Genetics of Alcoholism (COGA), we performed quantitative linkage analyses using a panel of 1717 SNPs. Genome-wide linkage analyses...

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Identifiers

PMID: 17942244
DOI: 10.1016/j.drugalcdep.2007.08.015
PMCID: PMC2266629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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